Tuesday, January 24, 2012

Cancer and Chromosomes - Again

Aneuploidy has been much neglected but is now gaining interest, possibly because after finding so many genetic alterations it has been realised that cancers are much more than about genes. There is one issue with this news release though. When they state:

"But in cancer, there are many cases of extra or missing chromosomes. Yet cancer cells thrive more effectively than other cells," Prof. Shamir says.

Yet in the paper I read the other day it was claimed that most cancer cells become senescent after 60-90 days(in their model at least). That makes sense because if a cell is being damaged or not working properly it will become senescent. Cancer cells don't thrive, the cancer stem cells may thrive, but even that is problematic. 

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