Saturday, October 2, 2010

Cannabis and Memory Loss

This finding from the British Journal of Psychiatry is very consistent with the known pharmacology of THC. It is found that the higher the THC content, the greater the memory loss. Modern breeds of marijuana undoubtedly have higher THC content, though this increase is greatly exaggerated by the authorities.

This modern change in the ratios of THC to CBD probably explains the rise in cannabis associated psychosis. This recent research piece, a nice piece of work, highlights the differing roles.

Wednesday, September 29, 2010

Blowing up Cancer Cells

Remarkably creative and clever approach to attacking cancer ...

In the zebra-fish study, Lapotko and his collaborators at Rice directed antibody-tagged gold nanoparticles into the implanted cancer cells. A short laser pulse overheated the surface of the nanoparticles and evaporated a very thin volume of the surrounding medium to create small vapor bubbles that expanded and collapsed within nanoseconds; this left cells undamaged but generated a strong optical scattering signal that was bright enough to detect a single cancer cell.
A second, stronger pulse generated larger nanobubbles that exploded (or, as the researchers called it, "mechanically ablated") the target cell without damaging surrounding tissue in the zebra fish. Scattering of the laser light by the second "killer" bubble confirmed the cellular destruction.

Friday, September 24, 2010

A Natural Response to Alzheimer's Disease

It was only a few years ago that most believed amyloid plaques and protein tangles could not be removed from the nervous system. We now know better and recent findings have important implications for our cerebral health. Over recent years there have been a number of studies highlighting that in contradiction to another once well established opinion, age associated cognitive impairment is not inevitable and there exist a wide range of strategies to ameliorate cognitive decline with aging. Achieving that goal, and in these days that is a realistic goal, is no easy task. It requires a variety of strategies but the long term pay offs are potentially enormous. This possibility first occurred to me on yet another afternoon when I had the energy of a bamboo deprived panda, I was flicking through TV stations and caught a glimpse of an interview with BF Skinner. He related that at his age, 85, he felt he was still going work but he stressed that throughout his life he had been very careful about his health. There is a very important for those who wish to live long and prosper: if that truly is your goal you had better start living towards that goal before you are 35 years old.

Friday, September 10, 2010

Patrick Lockerby: Arctic Ice Update

Every month or so Patrick provides update on the ice dynamics in the Arctic. Here is the latest report. Thanks Patrick!