Steve Wolfram on the Nature of Mathematics

A video clip where Wolfram argues for mathematics existing in many possible forms and types.

Don't Interrupt Me

Study: Brief interruptions spawn errors

Short interruptions – such as the few seconds it takes to silence that buzzing smartphone – have a surprisingly large effect on one's ability to accurately complete a task, according to new research led by Michigan State University.

In the good ol' days when I knew how to concentrate I also knew that maintaining concentration for extended periods often required the satisfaction in knowing I could continue uninterrupted for however long I chose to be focused on the task at hand. A small quiet place is one of the most important assets for good work.

The Good Things About Oxidation

Note:

This is incomplete but I really want to be done with it for now. Expect difficulties, provide criticism.

For decades we have been assailed with the evils of oxidation. This paper argues that we are mistaken, that oxidation is not always bad but is an adaptive mechanism to address pathological insults. It is a challenging and fascinating hypothesis. The author provides some interesting insights that help elucidate the current contradictions between cellular based studies and epidemiological studies, the former indicating benefits from antioxidants and the latter finding no evidence, or even evidence of harm, from heavy anti-oxidant loading.

Who is the Strongest?

It is strange the sort of things that pop into my inbox and draw my attention. An article from Psychcentral highlighted yet again why I expect mental illness treatment to remain problematic for sometime to come. The article is entitled,, "The Myth of the Strong Person.". 

Psychotherapy and Drugs: A Dangerous Combination?

Recent comments by baz on previous post have drawn me away from the endless reading that is slowly destroying my life and harkened me back to the original idea in relation to that post. My original thought was this:

The use of drugs simultaneously with psychotherapy has value but must be carefully managed. Inducing behavioral change in a patient whose mental state is under the influence of powerful drugs may instantiate the desired behavior change that can easily be lost once the drugs are discontinued simply because the behavior change was created in that context. 

Today I read this: 

Beware small positive studies. By Neuroskeptic.

When selective serotonin reuptake inhibitors (SSRIs) were introduced for depression, effect sizes greater than 1.0 were reported, which created their legacy as a wonder drug. Over the course of 20 years, the mean effect size of SSRIs decreased to around 0.3. A similar trend was demonstrated for cognitive-behavioral therapy.

Psychiatry, Psychology, and Philosophy

6/11/2012 3:31PM

One of the more puzzling features of the mental health profession is the refusal to engage in a rigourous analysis of their own assumptions. It is as if they ignore the warning of Bertrand Russell when he advised that one of the first goals in philosophy is to recognise that a problem exists. Psychiatry is wedded to an excessively reductionist view of behavior , it is as if they have never encountered the concept of emergent properties let alone realised that a bottom up approach to understanding a complex system is almost always doomed to fail when there are many variables in play. The brain is the penultimate complex system. (Perhaps, given we don't know what brains do it may turn out that the processes are very simple, like a series of reiterations of very simple processes.) The psychologists catch and grab and whatever therapy comes along until it is eventually seen to be just another therapy offering little more than the placebo effect. Carl Rogers may deserve more credit than he is given today. Paradoxically the placebo effect may be the principle benefit in many therapeutic interventions but of course neither psychiatrists or psychologists would admit that because that would constitute a problem for them. No-one likes having the foundations of their concepts challenged. It is painful and could demand a complete re-appraisal of a conceptual structure. Hard work.

Society Without God - Phil Zuckerman(Review)

Title: 

Society Without God: What the Least Religious Nations Can Tell Us About Contentment.

Author: 

Phil Zuckerman, Professor of Sociology at Pitzer College

Publisher: 

New York University Press. 

Phil Zuckerman does a good job in dismantling the common mis-perception that religion is essential for society. Focusing on Denmark and Sweden, two countries notably lacking in religious affiliation and influence, the author demonstrates how in these countries the lack of religiosity has not turned them into hell holes of depravity and chaos but rather are outstanding examples of peaceful societies where individuals can enjoy their environment without fear of being mugged or murdered.

The Age of Empathy - Frans De Waal(Review)

If you are one of the great many who subscribes to the view that nature is red in tooth and claw, that humans are fundamentally and biologically selfish and only culture constrains our selfish impulses, please read this book. After you have done that, send a copy to your local politician! By golly they certainly need huge doses of the author's wisdom and insight.

In many of the developed nations the last 30 years has been marked by a distinct cultural shift towards a more Ayn Rand type view of human behavior. I have no idea why anyone would trust a philosopher to instruct them about human behavior, it is like asking a child to create quantum mechanics.

Frans De Waal, in the great tradition of Darwin and all good science, seeks to enlighten us as to the origins of our behavior by referencing not theories and intuitions, but observations tempered by a rigorous empiricism. The Age of Empathy is an outstanding piece of work.  

The Mankind Project: Modern Man Mythologised

Warning: this is a rant. If you like the idea of rediscovering your masculinity then don't bother reading on because you will be offended in every paragraph. Later on in this post I will attempt to give a dispassionate analysis that addresses the philosophical underpinnings of The Mankind Project.

Sunshine, Pathogen Genocide, Vitamin D, Happiness, and Cognition

Immunology has long fascinated me. Somewhere, sometime I read how the immune system was so sensitive it could identify a self from non-self protein in as little as 10 amino acids. "Crap!" I internally exclaimed even though completely ignorant of immunology at that time. As it turns out ...

Sort of true. That is a class of molecular structures known as PAMPS: pathogen associated molecular patterns.  Charles Janeway is the poster boy on that front. Our innate immune system is sensitized to these patterns. When you crunch numbers in a crude off the top sort of way, the immune system does a remarkably good job at fending off pathogens that have certain mathematical advantages. The challenge is so great that evolution came up with(remarkably!) the heavy and light chains which allow a tremendous ongoing creation of antibody types until there is one that "fits". It is a numbers game and while there are good odds with microbes the odds are bad with viruses because their replication and mutation rates are, relatively speaking, much higher. Two modern viruses are excellent examples of this. Hepatitis C and HIV exist in a variety of variants that will keep expanding. So when you think of mass extinctions remember one viable cause is a tiny molecular structure of only two key components which can wipe out a species very quickly and leave no trace. It dies with the species. That is an unsuccessful virus and not our concern. We are concerned with all the bugs that manage to live on and in us.