Recent comments by baz on previous post have drawn me away from the endless reading that is slowly destroying my life and harkened me back to the original idea in relation to that post. My original thought was this:
The use of drugs simultaneously with psychotherapy has value but must be carefully managed. Inducing behavioral change in a patient whose mental state is under the influence of powerful drugs may instantiate the desired behavior change that can easily be lost once the drugs are discontinued simply because the behavior change was created in that context.
Today I read this:
Beware small positive studies. By Neuroskeptic.
When selective serotonin reuptake inhibitors (SSRIs) were introduced for depression, effect sizes greater than 1.0 were reported, which created their legacy as a wonder drug. Over the course of 20 years, the mean effect size of SSRIs decreased to around 0.3. A similar trend was demonstrated for cognitive-behavioral therapy.